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Fuzheng Yiliu Formula

Development stage: Unknown
Lead developer: Guangdong Provincial Hospital of Traditional Chinese Medicine
Administration: Oral

Overview

Fuzheng Yiliu Formula is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Guangdong Provincial Hospital of Traditional Chinese Medicine. It is primarily investigated for its potential to delay disease progression in patients with metastatic hormone-sensitive prostate cancer (mHSPC). In TCM theory, the formula is designed to strengthen the body's resistance (Fuzheng) and suppress tumors (Yiliu). It is typically administered as an oral decoction or granules alongside standard androgen deprivation therapy (ADT) to prevent or delay the transition to castration-resistant prostate cancer (CRPC).

Other names: Fuzheng Yiliu FangFZYLF

Targets

JUN (Transcription factor Jun)STAT3 (Signal Transducer and Activator of Transcription 3)RELA (Nuclear Factor Kappa B Subunit p65)PIK3CA (Phosphoinositide 3-kinase alpha)IGF-1R (Insulin-like growth factor 1 receptor)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)TP53 (Cellular Tumor Antigen p53 R175H)MYC (MYC proto-oncogene protein)MAPK3 (Mitogen-activated protein kinase 1)ESR1 (ERα)

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