Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
fuzhenghuayu granules
- Development stage
- Unknown
- Lead developer
- Baheal Pharma
- Administration
- Oral
01
Overview
Fuzhenghuayu granules is a Traditional Chinese Medicine (TCM) compound formula primarily developed for the treatment of organ fibrosis, particularly liver fibrosis and chronic kidney disease. The formula consists of six Chinese medicinal herbs: *Salvia miltiorrhiza* (Danshen), *Cordyceps sinensis* (Dongchongxiacao), *Prunus persica* (Taoren), *Gynostemma pentaphyllum* (Jiaogulan), *Pollen typhae* (Puhuang), and *Schisandra chinensis* (Wuweizi). It exerts anti-fibrotic effects by inhibiting the activation of myofibroblasts, reducing the expression of Transforming Growth Factor-beta 1 (TGF-β1), and promoting the degradation of the extracellular matrix. In clinical trials, it is often evaluated as an adjunctive therapy to standard treatments like losartan for chronic glomerulonephritis and chronic kidney disease to reduce proteinuria and preserve renal function. It was the first TCM formula to complete a Phase 2 clinical trial in the United States for liver fibrosis.
- Brand names
- Fuzhenghuayu
- Other names
- Fuzhenghuayu formulaFZHY granulesFuzhenghuayu capsule
02
Targets
SMAD3 (SMAD family member 3)TGFB1 (Transforming growth factor Beta-1 proprotein)SMAD2 (Mothers against decapentaplegic homolog 2)
Beyond the preview
Go deeper on fuzhenghuayu granules.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on fuzhenghuayu granules.