fuzhong xiaoji

Fuzhong Xiaoji is a Traditional Chinese Medicine (TCM) formula developed by Ruijin Hospital, affiliated with the Shanghai JiaoTong University School of Medicine, specifically for the treatment of colorectal cancer. It is primarily utilized as an adjuvant therapy to enhance the efficacy and reduce the toxicity of standard chemotherapy regimens such as XELOX (oxaliplatin and capecitabine). The formula is designed according to the TCM principles of Fuzhong (strengthening the body's resistance) and Xiaoji (eliminating accumulations or tumors). Clinical and preclinical studies suggest that Fuzhong Xiaoji works by modulating the host immune response, regulating the gut microbiota, and inhibiting pro-tumorigenic signaling pathways such as PI3K/Akt and Wnt/beta-catenin. It is typically administered as an oral decoction or in granule form and is a recognized hospital preparation within the Ruijin Hospital system.

Other names

Fuzhong Xiaoji formulaFuzhong Xiaoji decoctionFuzhong Xiaoji recipeFZXJF