G-1

G-1 is a selective agonist of the G protein-coupled estrogen receptor (GPER; formerly known as GPR30), distinct from classical estrogen receptors ERα and ERβ. It is primarily a research compound and is not approved as a pharmaceutical for clinical use. G-1 is used in preclinical studies to investigate the biological functions of GPER, including its roles in cell proliferation, cardiovascular function, metabolic regulation, and cancer biology. G-1 demonstrates high specificity for GPER, mediating rapid, non-genomic signaling pathways distinct from those of nuclear estrogen receptors. Users should not confuse G-1 with any pill or product simply marked G1 or G 1, which may refer to entirely different active ingredients (e.g., guanfacine, glycopyrrolate) depending on imprint[3][4].

Brand names

Tespria

Other names

G-1G1G 1