Drug intelligence / Profile preview

Ga68-Dolacga

Development stage
Unknown
Lead developer
National Atomic Research Institute
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Peptide-Drug Conjugates → Peptide Conjugates → Peptides, Small Molecules
Administration
Intravenous
01

Overview

Ga68-Dolacga is a radiopharmaceutical diagnostic agent used in positron emission tomography (PET) imaging, primarily developed for the evaluation of liver reserve function and tumor response in patients with hepatocellular carcinoma. It consists of a peptide chelated to gallium-68, a positron-emitting radionuclide. The agent is designed to target specific receptors or tissues within the liver, enabling functional imaging that can assess hepatic reserve before and after interventions such as proton therapy or surgery. Clinical studies have demonstrated its high liver-targeting properties and favorable safety profile[3][8]. The mechanism of action involves selective uptake by hepatic tissue, allowing quantitative assessment of regional liver function.

Brand names
Dolacga
Other names
Gallium Ga-68 DolacgaGa-68 DolacgaGa68 DolacgaGa 68 DolacgaGa68-Dolacga InjectionGa-68-Dolacga InjectionGa 68-Dolacga Injection

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