gadolinium-rhodamine human serum albumin nanoparticles

**Gadolinium-rhodamine human serum albumin nanoparticles** are multifunctional nanoparticles that combine gadolinium ions (Gd), a fluorescent dye (rhodamine), and human serum albumin (HSA) as the carrier matrix. These nanoparticles are primarily developed for **multimodal imaging applications**—combining magnetic resonance imaging (MRI) from gadolinium and fluorescent imaging via rhodamine. HSA serves as a biocompatible, long-circulating carrier that enhances plasma half-life, facilitates tumor targeting via the enhanced permeability and retention (EPR) effect, and leverages overexpressed albumin-binding proteins (e.g., SPARC, gp60) in many tumors for active delivery. These nanoparticles are also being explored as drug delivery systems or theranostic agents, allowing simultaneous imaging and therapy (e.g., photodynamic therapy if a photosensitizer is included). No commercial brand or code names for this specific formulation are listed in current literature. Most research has focused on **preclinical applications in cancer imaging and theranostics**[1].

Other names

Gd-Rhodamine-HSA nanoparticles