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GAIA-121-125 A+

Development stage: Preclinical
Lead developer: GAIA BioMedicine
Modality: CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration: Intravenous

Overview

GAIA-121-125 A+ is a preclinical-stage, allogeneic cellular immunotherapy developed by GAIA BioMedicine using its proprietary GAIA Antibody-Armed Adoptive cell therapy Platform (GAAAP). The therapy consists of NK-like cells derived from peripheral blood mononuclear cells (PBMCs) that are armed with proprietary antibodies. These antibodies are designed to recognize and bind to a specific, undisclosed tumor-associated antigen designated as 'antigen A+.' This binding directs the natural killer cell-mediated cytotoxicity specifically toward tumor cells expressing the A+ antigen. The product is designed as an 'off-the-shelf' intravenous treatment for solid tumors characterized by the presence of the A+ antigen.

Other names: GAAAP antibody-armed NK-like cell

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