Drug intelligence / Profile preview

galactomannan

Development stage
Unknown
Lead developer
Bio-Rad Laboratories
Administration
Oral
01

Overview

Galactomannan is a polysaccharide composed of a mannose backbone with galactose side chains. In the supplied clinical-trial context, the exact asset appears to be enterally administered galactomannan used as a nutritional fiber intervention in critically ill patients, including explicit mention of \"beta-galactomannan\" tube feeding and related PHGG-enriched enteral formulas. Rather than acting through a discrete receptor pharmacology typical of drugs, galactomannan functions as a soluble, non-digestible carbohydrate that can modulate gastrointestinal tolerance, stool characteristics, and gut microbiota through prebiotic fermentation and downstream short-chain-fatty-acid generation. The evidence provided supports real-world clinical investigation as a nutritional or nutraceutical intervention in critical illness and post-gastrointestinal-surgery enteral nutrition, but not as a conventional pharmaceutical therapeutic with a single sponsor-developed molecular drug program.

Other names
galactomannanbeta-galactomannan半乳甘露聚糖
02

Targets

LGALS1 (Galectin-1)

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