Drug intelligence / Profile preview

galactooligosaccharides + inulin

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Galactooligosaccharides + inulin is a combination of two well-studied prebiotic fibers. Both are non-digestible carbohydrates that selectively stimulate the growth and activity of beneficial gut bacteria, particularly Bifidobacteria and Lactobacilli. This combination has been investigated for its synergistic effects on gut health, immune modulation, and potential chemopreventive properties against colorectal cancer. In animal models, the combined use of GOS and inulin demonstrated greater inhibition of precancerous lesions (aberrant crypt foci) than either component alone[2]. In humans, these prebiotics are used to support digestive health, relieve constipation, modulate blood sugar levels (especially relevant for diabetes), promote mineral absorption (notably calcium), improve stool frequency/consistency, and potentially reduce risk factors associated with colon cancer[3][5][6]. The mechanism involves fermentation by colonic bacteria to produce short-chain fatty acids (SCFAs), which contribute to improved mucosal health and immune regulation.

Other names
GOS + inulinprebiotic combination of galactooligosaccharides and inulin

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