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galgeunhaegi-tang
- Development stage
- Unknown
- Lead developer
- Kyung Hee University
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Galgeunhaegi-tang (GHT) is a traditional Korean herbal medicine formula prescribed within Sasang constitutional medicine for the Taeeumin (TE) body type, specifically to treat Interior Heat patterns. The formula is a multi-herb decoction typically containing *Pueraria lobata* (Galgeun), *Scutellaria baicalensis*, *Ligusticum tenuissimum* (Gobon), *Platycodon grandiflorum*, and *Angelica dahurica*, among others. It is designed to resolve heat depression (鬱熱) and accompanying dryness (燥). Clinical and preclinical research has explored its potential in inhibiting tumor progression in non-small cell lung cancer (NSCLC), managing trigeminal neuralgia, and modulating immune responses. As a botanical preparation, it exerts multi-target effects, including anti-inflammatory and antioxidant activities, and is commonly administered as an oral decoction or in granule form.
- Other names
- GHTKalgunhaegi-tangGalgeunhaegi-tang
02
Targets
IL-6 (Interleukin 6)NF-κBTNFA (Tumor necrosis factor alpha (soluble))
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