Drug intelligence / Profile preview

gallium ga 68 FAP-CHX

Development stage
Phase 2
Lead developer
The First Hospital of Fujian Medical University
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

**Gallium ga 68 FAP-CHX** is a **fibroblast activation protein-targeted PET radiotracer** designed for **diagnostic PET/CT imaging** of tumors with FAP-expressing cancer-associated fibroblasts in the tumor microenvironment. It consists of the FAP-targeting small-molecule tracer FAP-CHX labeled with **gallium-68**, enabling visualization of FAP-positive stromal elements in cancer. Public sources verify a clinical study sponsored by **The First Hospital of Fujian Medical University** evaluating its safety, biodistribution, pharmacokinetics, radiation dosimetry, and diagnostic performance in patients with various solid tumors, including head-to-head comparison with **68Ga-FAPI-04** or **18F-FDG** PET/CT. This agent is a **diagnostic radiopharmaceutical**, not a therapeutic radioligand.

Other names
68Ga-FAP-CHXgallium Ga 68 FAP-CHXgallium Ga 68-FAP-CHX
02

Targets

FAP (Fibroblast activation protein alpha)

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