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gallium Ga-68 NOTA-SNA002
- Development stage
- Phase 1
- Lead developer
- SmartNuclide
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
- Administration
- Intravenous
01
Overview
Gallium Ga-68 NOTA-SNA002 is a radiotracer composed of SNA002, a targeting agent for programmed cell death ligand 1 (PD-L1; also known as cluster of differentiation 274 or CD274), conjugated to the chelator NOTA and labeled with the positron-emitting radioisotope gallium-68. It is designed for use in positron emission tomography (PET) imaging to detect PD-L1 expression in tumors. By binding specifically to PD-L1 on tumor cells, this agent enables non-invasive visualization and quantification of PD-L1 expression, which can be relevant for cancer diagnosis and potentially for guiding immunotherapy decisions[1].
- Other names
- SNA002SNA-002SNA 002
02
Targets
CD274 (Programmed cell death protein 1 ligand 1)
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