Drug intelligence / Profile preview

Galvecta Plus

Development stage
Phase 4
Lead developer
Clinision
Modality
Small Molecules
Administration
Oral
01

Overview

Galvecta Plus is a fixed-dose combination tablet containing vildagliptin and metformin hydrochloride, developed by Clinision for the treatment of type 2 diabetes mellitus. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the levels of incretin hormones, which in turn stimulates insulin production and reduces glucagon secretion in a glucose-dependent manner. Metformin is a biguanide that improves glycemic control by decreasing hepatic glucose production and increasing peripheral glucose uptake and utilization. This combination therapy is indicated for patients with type 2 diabetes who are inadequately controlled by diet and exercise alone or by metformin monotherapy.

Brand names
Galvecta Plus
Other names
metformin + vildagliptinvildagliptin + metformin
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)DPP-4 (Dipeptidyl Peptidase-IV)

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