Drug intelligence / Profile preview

GAMAMIK NT-TAB

Development stage
Unknown
Lead developer
Vin Medicament
Modality
Small Molecules
Administration
Oral
01

Overview

GAMAMIK NT-TAB is an oral combination pharmaceutical product marketed by Vin Medicament for the management of pain and inflammatory conditions, specifically targeting neuropathic pain. The medication consists of two active small molecule ingredients: gabapentin and nortriptyline. Gabapentin acts by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, thereby reducing the release of excitatory neurotransmitters. Nortriptyline, a tricyclic antidepressant, complements this action by inhibiting the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. This dual-action approach is commonly utilized for chronic conditions such as diabetic peripheral neuropathy and postherpetic neuralgia.

Brand names
GAMAMIK NT-TAB
02

Targets

SERT (Sodium-dependent serotonin transporter)CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)NET (Norepinephrine Transporter)

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