Drug intelligence / Profile preview

gamma-aminobutyric acid tartarate + glutamic acid + dibasic calcium phosphate + thiamine nitrate + pyridoxine chloride + cyanocobalamin

Development stage
Phase 4
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

This is a fixed-dose combination product containing gamma-aminobutyric acid (GABA) tartarate, glutamic acid, dibasic calcium phosphate (as a source of calcium), thiamine nitrate (vitamin B1), pyridoxine chloride (vitamin B6), and cyanocobalamin (vitamin B12). The combination is designed to address neurological symptoms and support nervous system health. GABA acts as an inhibitory neurotransmitter in the central nervous system, while glutamic acid serves as an excitatory neurotransmitter. Calcium supports neuronal function. Thiamine, pyridoxine, and cyanocobalamin are essential B vitamins involved in nerve metabolism, myelin synthesis, and cellular energy production. This combination has been studied for the management of chronic complaints consistent with motion sickness and has shown efficacy in reducing symptoms compared to ginger extract[1][2]. The components also have established roles in treating or preventing vitamin deficiencies and supporting nerve health.

Brand names
GevitGevit-L
Other names
gamma-aminobutyric acid tartrate and associations
02

Targets

MTR (Methionine synthase)TPK1 (Thiamine pyrophosphokinase 1)PDXK (Pyridoxal kinase)GABAA (Gamma-aminobutyric acid receptor)

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