Gan-Lu-Yin

Gan-Lu-Yin is a traditional Chinese herbal formula composed of multiple herbs and used primarily for its anti-inflammatory and detoxifying properties. It is indicated for oral inflammatory conditions such as periodontitis, stomatitis, glossodynia (burning mouth syndrome), chronic pharyngitis, gingivitis, mouth ulcers, sore throat, gum atrophy and swelling. The formula is also used in modern practice as an adjunct therapy in cancer care (notably liver cancer and oral cancer) due to proposed anti-angiogenic effects that may inhibit tumor growth. Additionally, it has been studied for use in autoimmune diseases such as Sjögren’s syndrome and lupus. Mechanistically, Gan-Lu-Yin acts by reducing pro-inflammatory cytokines including IL-1β, IL-6 and TNF-α; inhibiting COX-2 expression; suppressing NF-κB signaling; decreasing osteoclast differentiation to reduce bone resorption; exerting broad-spectrum bacteriostatic effects against pathogens involved in oral disease; modulating immunity via components like Dendrobium officinale polysaccharide. Its ingredients include Radix Rehmanniae praeparata (shu di huang), Radix Ophiopogonis (mai men dong), Fructus Aurantii (zhi ke), Radix Glycyrrhizae praeparata cum melle (zhi gan cao), Herba Artemisiae capillaris (yin chen hao), Folium Eriobotryae (pi pa ye), Herba Dendrobii fimbriati (shi hu), Radix Scutellariae baicalensis (huang qin), Radix Rehmanniae glutinosae recens/sheng di huang) and Radix Asparagi cochinchinensis/tian men dong[2][3][4][5][6].

Brand names

Gan Lu YinSweet Combination

Other names

甘露飲Kanro In (Japanese)Sweet Dew Drink