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Ganlu Qingwen
- Development stage
- Phase 1
- Lead developer
- Yiling Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Ganlu Qingwen is a Traditional Chinese Medicine (TCM) granule formulation developed by the Fourth Affiliated Hospital of Xinjiang Medical University (also known as the Affiliated TCM Hospital of Xinjiang Medical University). Originally formulated to treat community-acquired pneumonia (CAP) and acute lung injury (ALI), it gained significant prominence during the COVID-19 pandemic as a regional treatment protocol in Xinjiang, China. The preparation is designed to clear heat, resolve dampness, and detoxify. Pharmacologically, it is reported to reduce systemic inflammation by downregulating pro-inflammatory cytokines such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α), thereby mitigating the cytokine storm associated with severe viral pneumonia and lung injury. It is officially approved as a hospital preparation (医院制剂) in the Xinjiang Uygur Autonomous Region.
- Brand names
- Ganlu Qingwen
- Other names
- Ganlu Qingwen GranulesGanlu Qingwen FormulaGanlu Qingwen Keli
02
Targets
NF-κBNLRP3 (Nod-like receptor family pyrin domain-containing protein 3)STAT3 (Signal Transducer and Activator of Transcription 3)TNFA (Tumor necrosis factor alpha (soluble))
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