Drug intelligence / Profile preview

Ganlu Qingwen

Development stage
Unknown
Lead developer
Yiling Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Ganlu Qingwen is a Traditional Chinese Medicine (TCM) granule formulation developed by the Fourth Affiliated Hospital of Xinjiang Medical University (also known as the Affiliated TCM Hospital of Xinjiang Medical University). Originally formulated to treat community-acquired pneumonia (CAP) and acute lung injury (ALI), it gained significant prominence during the COVID-19 pandemic as a regional treatment protocol in Xinjiang, China. The preparation is designed to clear heat, resolve dampness, and detoxify. Pharmacologically, it is reported to reduce systemic inflammation by downregulating pro-inflammatory cytokines such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α), thereby mitigating the cytokine storm associated with severe viral pneumonia and lung injury. It is officially approved as a hospital preparation (医院制剂) in the Xinjiang Uygur Autonomous Region.

Brand names
Ganlu Qingwen
Other names
Ganlu Qingwen GranulesGanlu Qingwen FormulaGanlu Qingwen Keli
02

Targets

NF-κBNLRP3 (Nod-like receptor family pyrin domain-containing protein 3)TNFA (Tumor necrosis factor alpha (soluble))STAT3 (Signal Transducer and Activator of Transcription 3)

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