Drug intelligence / Profile preview

ganlu xiaodu dan

Development stage
Preclinical
Lead developer
Southern Medical University
Administration
Oral
01

Overview

Ganlu xiaodu dan (also known as Ganlu Xiaodu Decoction or Ganlu Xiaodu Pills) is a traditional Chinese medicine (TCM) herbal formula widely used to clear heat, resolve dampness, and detoxify the body. It is traditionally indicated for damp-heat seasonal epidemic patterns, presenting with symptoms such as fever, fatigue, chest tightness, sore throat, and abdominal distension. The formula typically consists of eleven herbal ingredients: Talcum (Huashi), Scutellaria baicalensis (Huangqin), Artemisia capillaris (Yinchen), Acorus calamus (Shichangpu), Fritillaria cirrhosa (Chuanbeimu), Akebia trifoliata (Mutong), Pogostemon cablin (Huoxiang), Forsythia suspensa (Lianqiao), Belamcanda chinensis (Shegan), Amomum villosum (Shaoren), and Mentha haplocalyx (Bohe). It has been evaluated in clinical trials for preventing suboptimal health status in individuals with a biased damp-heat constitution, and has also been studied for its potential antiviral and anti-inflammatory effects in respiratory infections such as viral pneumonia and COVID-19.

Other names
Ganlu Disinfection PillGanlu Xiaodu DecoctionGanlu Xiaodu PillsSweet Dew Disinfecting PelletsSweet Dew to Eliminate Toxin Pellet
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)CASP3 (Caspase-3)EGFR (Epidermal growth factor receptor)JNK (Mitogen-activated protein kinase kinase kinase family)PIK3CA (Phosphoinositide 3-kinase alpha)STAT3 (Signal Transducer and Activator of Transcription 3)TP53 (Cellular Tumor Antigen p53 R175H)

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