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ganmaoan
- Development stage
- Unknown
- Lead developer
- Changhai Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Ganmaoan (also referred to as Ganmao'an) is a combination pharmaceutical product widely utilized in China for the treatment of the common cold and upper respiratory tract infections. Typically formulated as granules, it integrates Western active pharmaceutical ingredients with Traditional Chinese Medicine (TCM) herbal extracts. The standard formulation includes paracetamol (acetaminophen) for its analgesic and antipyretic properties, chlorpheniramine maleate as an antihistamine to alleviate nasal symptoms, and caffeine, alongside botanical extracts such as *Isatis tinctoria* (Banlangen), *Lonicera japonica* (Jinyinhua), and *Chrysanthemum indicum* (Yejuhua). Ganmaoan has been the subject of clinical investigation, notably by The First Affiliated Hospital of Naval Medical University, to evaluate its efficacy in managing clinical symptoms in patients with non-severe COVID-19, specifically those infected with the Omicron variant.
- Brand names
- Ganmaoan
- Other names
- Ganmao'anGanmaoan GranulesGanmao'an Granules
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HRH1 (Histamine H1 Receptor)
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