Drug intelligence / Profile preview

Ganoderma tsugae ethanol extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Ganoderma tsugae ethanol extract is a bioactive preparation derived from the fruiting body of the medicinal mushroom Ganoderma tsugae using an ethanol extraction process. It is rich in triterpenoids such as platycodigenin, cucurbitacin IIb, and ganolecidic acid B[1][5]. Preclinical studies have demonstrated that this extract exhibits hepatoprotective effects by reducing oxidative stress and inflammation in models of liver injury[1][5]. Additionally, it has shown anti-cancer activity against metastatic prostate cancer cells by inhibiting cell proliferation and metastasis through blockade of the PI3K/Akt and MAPK/ERK signaling pathways and induction of caspase-dependent apoptosis[2]. The product is primarily investigated as a functional food or dietary supplement with potential applications for liver protection and adjunctive cancer therapy.

Other names
GTEEGanoderma tsugae extractGT ethanol extractGTE
02

Targets

MAPK3 (Mitogen-activated protein kinase 1)

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