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Drug intelligence / Profile preview
GanShenAn
- Development stage
- Phase 4
- Lead developer
- Shuguang Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
GanShenAn is a Traditional Chinese Medicine (TCM) herbal formula developed by Shuguang Hospital, affiliated with the Shanghai University of Traditional Chinese Medicine, for the treatment of type 2 diabetes mellitus (T2DM). It is specifically formulated to address the TCM syndrome of liver-yin and kidney-yin deficiency, a common pattern in chronic metabolic disorders. The formula is designed to regulate blood glucose levels, improve insulin sensitivity, and alleviate clinical symptoms such as fatigue, thirst, and lower back soreness. Pharmacological research indicates that GanShenAn exerts its therapeutic effects by modulating glucose and lipid metabolism, potentially through the activation of the PI3K/Akt signaling pathway and the protection of pancreatic islet beta-cell function. It is typically administered as an oral granule or capsule and is utilized as a hospital preparation within the developer's clinical network.
- Brand names
- GanShenAn
- Other names
- GanshenanGan-Shen-An
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)PI3K (Phosphoinositide-3-kinase regulatory subunit 6)INSR (Insulin receptor)AKT (RAC-alpha serine/threonine-protein kinase)
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