Drug intelligence / Profile preview

ganzaoning

Development stage
Unknown
Lead developer
Shanghai Changhai Hospital
Administration
Oral
01

Overview

Ganzaoning is a Traditional Chinese Medicine (TCM) herbal formulation, typically administered as a granule, developed by Shanghai Changhai Hospital (also known as the First Affiliated Hospital of the Naval Medical University). It is primarily indicated for the treatment of chronic liver conditions, specifically chronic hepatitis B virus (HBV) infection and non-alcoholic fatty liver disease (NAFLD). The formulation is designed to reduce liver fat content and improve liver-related biochemical parameters. As a multi-herb TCM product, its therapeutic effect is likely mediated through multiple pathways, including the modulation of lipid metabolism and the reduction of hepatic inflammation. It has been evaluated in prospective, randomized, double-blind, placebo-controlled clinical trials to assess its efficacy in patients with concomitant HBV and NAFLD.

Brand names
Ganzaoning
Other names
Ganzaoning granuleGanzaoning granules
02

Targets

HSP90AA1 (Heat shock protein HSP90-alpha)RELA (Nuclear Factor Kappa B Subunit p65)IL17RA (IL-17RA)JUN (Transcription factor Jun)

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