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Ganzhixiao is a Traditional Chinese Medicine (TCM) herbal formulation developed for the treatment of metabolic associated fatty liver disease (MAFLD), particularly the damp-heat syndrome type. Typically administered in capsule form, the formula is designed to reduce hepatic steatosis and improve metabolic parameters. Clinical evaluation, including Phase 2 randomized trials, has utilized MRI-proton density fat fraction (MRI-PDFF) as a primary endpoint to measure its efficacy in reducing liver fat content. The development and clinical study of Ganzhixiao are notably associated with researchers such as Dong Hui at Tongji Hospital of Huazhong University of Science and Technology.
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