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Gardasil 9 + hepatitis B vaccine + cognitive behavioral therapy
- Development stage
- Unknown
- Lead developer
- Merck
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
This multimodal intervention protocol, spearheaded by Eunice Dube, is designed to address the high burden of Hepatitis B (HBV) and Human Papillomavirus (HPV) related cancers in Zimbabwe. The approach combines the administration of the Gardasil 9 vaccine (targeting nine HPV types) and a standard Hepatitis B virus vaccine with Cognitive Behavioral Therapy (CBT). The program targets women of childbearing age and young adults, aiming to provide primary prevention against cervical and liver cancers while simultaneously addressing mental health concerns like depression and anxiety through behavioral intervention. This multifaceted strategy seeks to improve vaccine uptake and overall health outcomes in a resource-limited setting by integrating preventive immunization with psychological support.
- Brand names
- Gardasil 9Gardasil9Gardasil-9
- Other names
- HBV vaccineHPV vaccineCognitive Behavioral TherapyCBT
02
Targets
HPV16 (Human papillomavirus type 16)HPV45 L1HPV31 L1HPV33 L1HBsAg (Hepatitis B surface antigen)HPV58 L1 (Human papillomavirus type 58 major capsid protein L1)HPV6 L1 (Human papillomavirus type 6 major capsid protein L1)HPV11 L1HPV52 L1 (Human papillomavirus type 52 major capsid protein L1)HPV18 L1
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