Drug intelligence / Profile preview

gardenia jasminoides fruit extract

Development stage
Preclinical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Gardenia jasminoides fruit extract is a botanical extract derived from the fruit of the Gardenia jasminoides plant, traditionally used in East Asian medicine and incorporated into cosmetic and food products. Its primary bioactive compounds include iridoids (e.g., geniposide, genipin, gardenoside), crocins (carotenoid pigments), flavonoids, and various volatile oils[1][2]. These constituents confer antioxidant, anti-inflammatory, and skin-soothing properties, making the extract beneficial in skincare for calming irritation and protecting against environmental stressors[1][9]. In addition to its medicinal uses, Gardenia jasminoides fruit extract serves as a natural colorant in foods and cosmetics, producing hues from yellow (via crocin) to blue (via genipin reacting with amino acids), and green or reddish-purple shades depending on formulation conditions[1]. Pharmacologically, the extract has demonstrated hepatoprotective, anti-fibrotic, and gastroprotective effects in animal models, notably modulating inflammatory pathways (e.g., suppression of NF-κB, TGF-β1, α-SMA, and collagen expression) and increasing protective factors like prostaglandin E2 and mucin 5AC in the stomach[3][8]. It is also investigated for effects on metabolic disorders, liver fibrosis, and as an antioxidant with possible melatonin-like activity in cosmetics[3][7]. Gardenia jasminoides fruit extract is not a single-molecule pharmaceutical but a complex mixture whose effects are attributed to the combination of its phytochemical constituents[1][2].

Other names
Gardenia fruit extractGJEGardenia extractGardenia jasminoides Ellis fruit extractCape Jasmine fruit extractCape Jessamine fruit extractDanh DanhFleur JauneGardenia augusta fruit extractGardenia florida fruit extractGardenia radicans fruit extractJasmin do Cabo fruit extractJasmin du Cap fruit extractVarneria augusta fruit extractZhi ZiZhi Zi extract
02

Targets

TGFB1 (Transforming growth factor Beta-1 proprotein)NF-κBNOS2 (Nitric Oxide Synthase 2)PGE2 (Prostaglandin E2)TLR4 (Toll-like receptor 4)MUC5AC (Mucin-5AC)

Beyond the preview

Go deeper on gardenia jasminoides fruit extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on gardenia jasminoides fruit extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call