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garlic extract
- Development stage
- Phase 3
- Modality
- Small Molecules
- Administration
- Oral, Topical
01
Overview
Garlic extract is a dietary supplement derived from the bulbs of *Allium sativum*. It has been used traditionally and in modern herbal medicine for cardiovascular health—including lowering blood pressure and cholesterol—and as an immunostimulant. Mechanistically, garlic extract exhibits hypolipidemic (lipid-lowering), antioxidant, antithrombotic (reducing blood clot formation), anti-inflammatory effects and may inhibit enzymes involved in cholesterol metabolism such as microsomal triglyceride transfer protein (MTP) and acyl-CoA:cholesterol acyltransferase (ACAT). These actions contribute to its potential benefits in atherosclerosis and hypertension. Garlic extracts are available in various forms including standardized tablets/capsules and aged extracts[3][4][5][6].
- Brand names
- AilAjoCamphor of the PoorDasuanKnoblauchLa-suanNectar of the GodsPoor man's TreacleRust TreacleStinking Rose
- Other names
- garlic extractAllium sativum
02
Targets
CEL (Carboxyl ester lipase)MTTP (Microsomal triglyceride transfer protein large subunit)SOAT1 (Sterol O-acyltransferase)
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