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GASOKEY-DSR
- Development stage
- Unknown
- Lead developer
- JoY Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
GASOKEY-DSR is a branded generic fixed-dose combination medication marketed by JoY Pharma for the management of gastrointestinal conditions such as gastroesophageal reflux disease (GERD), dyspepsia, and peptic ulcers. It consists of two active ingredients: pantoprazole and domperidone. Pantoprazole is a proton pump inhibitor (PPI) that suppresses gastric acid production by covalently binding to and inhibiting the H+/K+-ATPase enzyme system at the secretory surface of the gastric parietal cell. Domperidone is a peripheral dopamine D2 receptor antagonist that functions as a prokinetic agent, increasing lower esophageal sphincter pressure and accelerating gastric emptying. The "DSR" designation indicates a sustained-release formulation, typically applied to the domperidone component to provide prolonged therapeutic effects and allow for once-daily dosing.
- Brand names
- GASOKEY-DSR
- Other names
- pantoprazole + domperidone SR
02
Targets
DRD2 (Dopamine D2 Receptor)ATP4A (Potassium–transporting ATPase alpha chain 1)
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