Drug intelligence / Profile preview

gatifloxacin

Development stage
Approved
Lead developer
Kyorin Pharmaceutical
Modality
Small Molecules
Administration
Intravenous, Ophthalmic, Oral
01

Overview

Gatifloxacin is a fourth-generation fluoroquinolone antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for DNA replication, transcription, and repair. Developed by Kyorin Pharmaceutical Co., Ltd., it is used to treat various infections, including respiratory and urinary tract infections. Gatifloxacin is noted for its low phototoxicity and minimal toxicity to human cells.

Brand names
ZymarZymaxid
Other names
加替沙星
02

Targets

DNA gyraseTopo IV (Bacterial Topoisomerase IV)

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