gatifloxacin + prednisolone acetate

Gatifloxacin + prednisolone acetate is a fixed-dose combination ophthalmic medication used primarily to treat bacterial eye infections and to reduce inflammation in the eye, especially after surgery or in cases of uveitis, injury, or chemical burns. Gatifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic that acts by inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This results in bactericidal activity against both Gram-positive and Gram-negative bacteria. Prednisolone acetate is a corticosteroid that reduces inflammation by blocking the production of inflammatory mediators such as prostaglandins. The combination provides both antimicrobial action (from gatifloxacin) and anti-inflammatory effects (from prednisolone), making it effective for managing post-surgical or infectious ocular conditions[1][2][3][5][6].

Brand names

Gatiquin-PGat PPredzyNZ PredArogat-PAkrogat PVatiflo-PGate PGatiray P

Other names

gatifloxacin and prednisolone ophthalmic