Drug intelligence / Profile preview

GB-AOS12

Development stage
Preclinical
Lead developer
GlycosBio
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

GB-AOS12 is a preclinical-stage therapeutic candidate developed by GlycosBio for the treatment of pruritus (itch). It is formulated using the company's proprietary Activated Oil System (AOS), a lipid-based delivery technology designed to enhance the stability and biological activity of specific oils. The AOS platform aims to address skin health by modulating inflammatory and sensory pathways associated with chronic itch and irritation. As part of the GB-AOS series, which includes assets GB-AOS8 through GB-AOS12, this candidate is currently undergoing preclinical evaluation to establish its efficacy and safety profile for dermatological applications.

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