Drug intelligence / Profile preview

GB600

Development stage
Preclinical
Lead developer
GalleonBio
Modality
Small Molecules
01

Overview

GB600 is an investigational small molecule drug candidate being developed by Galleon Bio for the treatment of diabetic neuropathy. It is part of a pipeline of strontium-based therapies that utilize the strontium ion (Sr2+) to address chronic pain and inflammatory conditions. While specific chemical details for GB600 are limited, the Galleon Bio platform focuses on the therapeutic potential of strontium as a modulator of the calcium-sensing receptor (CaSR) and an inhibitor of transient receptor potential (TRP) channels, such as TRPV1, which are involved in the transmission of neuropathic pain. GB600 represents a targeted application of this strontium technology specifically for the management of pain associated with diabetic nerve damage.

02

Targets

CaSR (Extracellular calcium-sensing receptor)TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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