Drug intelligence / Profile preview

GBP511

Development stage
Phase 2
Lead developer
SK bioscience
Modality
Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

GBP511 is a universal coronavirus (pan-sarbecovirus) vaccine candidate developed by SK bioscience in collaboration with the University of Washington's Institute for Protein Design. It utilizes self-assembling protein nanoparticle technology to present viral antigens, specifically targeting the sarbecovirus family to provide broad protection against SARS-CoV-2 and related viruses. The program is supported by the Coalition for Epidemic Preparedness Innovations (CEPI) and is being evaluated in Phase 1/2 clinical trials, often in combination with the adjuvant CAS-1.

Other names
pan-sarbecovirus vaccineuniversal coronavirus vaccineSK bioscience universal coronavirus vaccine
02

Targets

BCR (Immunoglobulin G B Cell Receptor)T-cell receptor recognizing Guanylate-binding protein 5-derived peptides

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