Drug intelligence / Profile preview

GBP560

Development stage
Phase 2
Lead developer
SK bioscience
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

GBP560 is an mRNA-based vaccine candidate developed by SK bioscience for the prevention of Japanese encephalitis virus (JEV) infection. Developed in partnership with the Coalition for Epidemic Preparedness Innovations (CEPI), GBP560 serves as a prototype to validate an mRNA vaccine platform designed for rapid response to future pandemic threats, often referred to as "Disease X," under the "100 Days Mission" framework. The vaccine is currently being evaluated in Phase I/II clinical trials to assess its safety, reactogenicity, and immunogenicity in healthy adults. The collaboration aims to ensure equitable global access, prioritizing vaccine supply for low- and middle-income countries.

Other names
SK Japanese Encephalitis mRNA Vaccine
02

Targets

Japanese encephalitis virus Envelope protein / prM-E complex

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