Drug intelligence / Profile preview

GCB70

Development stage
Unknown
Lead developer
Chemical Resources
Modality
Small Molecules
Administration
Oral
01

Overview

GCB70 is a branded, clinically evaluated green coffee bean extract standardized to contain 70% chlorogenic acids (notably high in 5-caffeoylquinic acid) and less than 1% caffeine. It is marketed as a natural plant concentrate for healthy weight management and metabolic support. Clinical studies have shown that supplementation with GCB70 can significantly reduce body weight, BMI, waist circumference, plasma leptin levels, fasting glucose levels, HbA1c, and thyroid-stimulating hormone (TSH) over a period of 12 weeks in overweight or obese adults. The product has demonstrated broad-spectrum safety in clinical trials. Its primary mechanism is attributed to the effects of chlorogenic acids on glucose metabolism and fat oxidation[1][2][5][6][7].

Brand names
GCB70GCB-70GCB 70
Other names
green coffee bean extract (GCB70)green coffee bean extract with 70% chlorogenic acids
02

Targets

NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)G6PC1 (Glucose 6-phosphatase alpha)

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