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GCFLU Quadrivalent (GC Biopharma Corp)

Development stage
Unknown
Lead developer
GC Biopharma
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

GCFLU Quadrivalent is a quadrivalent, inactivated, egg-derived, split-virion influenza vaccine developed by GC Pharma (formerly Green Cross Corporation). It contains 15 µg of hemagglutinin (HA) antigen from each of four influenza virus strains: two influenza A subtypes (H1N1 and H3N2) and two influenza B lineages (Yamagata and Victoria), for a total of 60 µg per 0.5 mL dose. The vaccine works by inducing the immune system to produce antibodies against the viral hemagglutinin protein, thereby preventing the virus from attaching to and infecting host cells. Approved by South Korea's Ministry of Food and Drug Safety in 2015 for adults and in 2018 for children as young as 6 months, it is used for the prevention of seasonal influenza. A newer formulation, GC3110B, has been evaluated in Phase 3 clinical trials to confirm its safety and immunogenicity compared to the original formulation.

Brand names
GCFLU Quadrivalent
Other names
Green Cross Quadrivalent Influenza Vaccine
02

Targets

HA (Hemagglutinin)

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