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Gd-GQD
- Development stage
- Preclinical
- Lead developer
- Anhui University
- Modality
- Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
Gd-GQD refers to *gadolinium-doped graphene quantum dots*, engineered nanomaterials in which gadolinium (Gd), a paramagnetic metal, is incorporated into graphene quantum dots (GQDs)[3][4]. These structures are designed primarily as advanced magnetic resonance imaging (MRI) contrast agents, capitalizing on the paramagnetic properties of gadolinium and the small size, water dispersibility, and traceability of GQDs[3][4]. Gd-GQDs demonstrate **significantly enhanced longitudinal relaxivity** compared to commercial Gd-based MRI agents (e.g., Gd-DTPA), providing improved image contrast at lower concentrations[3][4]. The GQD scaffold also enables additional functionalities for targeted delivery, dual-modal (fluorescence plus MRI) imaging, and possible nanotheranostic applications (e.g., in cancer therapy)[4].
- Other names
- Gadolinium-doped graphene quantum dotsGd-doped GQDSAGd-GQDsparamagnetic graphene quantum dots
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