Drug intelligence / Profile preview

Gdue

Development stage
Unknown
Lead developer
Aesculapius
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Gdue is a dietary supplement developed by Aesculapius Farmaceutici, formulated to support glycemic control and body weight management. It contains InSea2®, a proprietary, polyphenol-rich phytocomplex extracted from the brown seaweeds *Ascophyllum nodosum* and *Fucus vesiculosus*, combined with chromium picolinate. Gdue acts as a dual inhibitor of alpha-amylase and alpha-glucosidase, the primary digestive enzymes responsible for carbohydrate breakdown, thereby slowing down glucose absorption and reducing postprandial blood glucose and insulin spikes. It is primarily used as a nutritional support to improve insulin sensitivity, manage blood sugar levels, and assist in weight loss or metabolic syndrome management.

Brand names
Gdue
Other names
GDUE
02

Targets

AMY (Pancreatic alpha-amylase)Sucrase-Isomaltase

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