general anesthesia

General anesthesia, in the context of the Peking University First Hospital clinical trial (NCT01640262), refers to a standard anesthetic regimen used as a comparator against combined epidural-general anesthesia in elderly patients undergoing surgery for malignant solid tumors. This specific protocol involves induction with the intravenous anesthetic propofol, maintenance of anesthesia using propofol and/or the volatile inhalational agent sevoflurane, and postoperative pain management via intravenous morphine. The study aims to determine if the choice of anesthetic technique influences long-term oncological outcomes, such as 5-year survival and cancer recurrence, by potentially modulating the perioperative stress response and immune function.

Other names

General anesthesia and postoperative intravenous analgesia