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GeneXSTEM
- Development stage
- Phase 2
- Lead developer
- BioIntegrate
- Modality
- Gene Therapies, Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
GeneXSTEM (GXS-001) is an autologous, gene-modified mesenchymal stem cell (MSC) therapy developed by GeneXstem Inc. for the treatment of degenerative joint diseases, specifically knee osteoarthritis. The therapy utilizes the patient's own adipose-derived stem cells, which are harvested and then genetically modified using a proprietary gene-delivery system to enhance their therapeutic potential. These modified cells are designed to overexpress specific growth factors or anti-inflammatory proteins that promote the regeneration of damaged cartilage and modulate the intra-articular inflammatory environment. By delivering a sustained therapeutic effect directly to the joint, GeneXSTEM aims to reduce pain, improve joint function, and potentially reverse the progression of osteoarthritis, offering a regenerative alternative to conventional symptomatic treatments.
- Other names
- GeneXstem therapyGeneXstem stem cell therapy
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