Drug intelligence / Profile preview

GenHevac-B

Development stage
Phase 4
Lead developer
Sanofi
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular, Intradermal
01

Overview

GenHevac-B is a recombinant hepatitis B vaccine that contains pre-S2 and S antigens of the Hepatitis B virus. It is designed to stimulate the immune system to produce anti-HBs antibodies, thereby providing protection against Hepatitis B virus infection. The vaccine has been investigated for both prophylactic use in HIV-infected patients, where standard vaccination protocols are often less effective, and for therapeutic purposes in individuals with chronic Hepatitis B infection, including inactive HBsAg carriers and those in the immune tolerant phase of chronic HBV infection.

Brand names
GenHevac-B
Other names
Genevac-B
02

Targets

BCR (B-cell receptor specific for HBsAg and pre-S2 epitopes)Hepatitis B virus pre-S2 domainHBsAg (Hepatitis B surface antigen)

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