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GenHevac-B
- Development stage
- Phase 4
- Lead developer
- Sanofi
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular, Intradermal
01
Overview
GenHevac-B is a recombinant hepatitis B vaccine that contains pre-S2 and S antigens of the Hepatitis B virus. It is designed to stimulate the immune system to produce anti-HBs antibodies, thereby providing protection against Hepatitis B virus infection. The vaccine has been investigated for both prophylactic use in HIV-infected patients, where standard vaccination protocols are often less effective, and for therapeutic purposes in individuals with chronic Hepatitis B infection, including inactive HBsAg carriers and those in the immune tolerant phase of chronic HBV infection.
- Brand names
- GenHevac-B
- Other names
- Genevac-B
02
Targets
HBsAg (Hepatitis B surface antigen)Hepatitis B virus pre-S2 domainBCR (B-cell receptor specific for HBsAg and pre-S2 epitopes)
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