Drug intelligence / Profile preview

GenSciP-111

Development stage
Preclinical
Lead developer
Changchun GeneScience Pharmaceutical
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Parenteral
01

Overview

GenSciP-111 is a **preclinical siRNA therapeutic candidate** reported to be developed by **Changchun Genescience Pharmaceuticals** for **idiopathic pulmonary fibrosis**. Publicly accessible drug-database information identifies it as an inhibitor of **connective tissue growth factor**, also known as **cellular communication network factor 2**, implying an RNA-interference mechanism intended to reduce CTGF expression and thereby attenuate profibrotic signaling and extracellular matrix deposition in fibrotic lung disease. No public clinical-trial record, regulatory approval, or detailed sequence-level disclosure was identified in the sources reviewed, so the program appears to remain an early-stage, sparsely described asset.

02

Targets

CTGF (Connective tissue growth factor)

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