Drug intelligence / Profile preview

Gensulin M30

Development stage
Unknown
Lead developer
BIOTON
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Gensulin M30 is a premixed, biphasic suspension of recombinant human insulin containing 30% soluble (rapid-acting) and 70% isophane (intermediate-acting) insulin. It is produced using recombinant DNA technology in E. coli, resulting in an amino acid sequence identical to endogenous human insulin. The drug is indicated for the treatment of diabetes mellitus in patients requiring exogenous insulin to maintain glucose control, including gestational diabetes. Its mechanism of action involves binding to the insulin receptor on target cells (such as muscle and adipose tissue), promoting cellular uptake of glucose from the bloodstream and inhibiting hepatic glucose production. This dual-phase formulation provides both rapid onset and prolonged duration of glycemic control[1][3][6].

Brand names
Gensulin M30
Other names
biphasic human insulin 30/70premixed recombinant human insulin 30/70
02

Targets

INSR (Insulin receptor)

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