Drug intelligence / Profile preview

gentamicin + dexamethasone

Development stage
Unknown
Modality
Small Molecules
Administration
Ophthalmic, Otic, Intratympanic
01

Overview

Gentamicin + dexamethasone is a combination medication consisting of gentamicin (an aminoglycoside antibiotic) and dexamethasone (a corticosteroid). Gentamicin works by preventing bacterial protein synthesis, effectively stopping bacterial growth. It is active against a wide variety of gram-negative and gram-positive bacteria, including Pseudomonas aeruginosa, Staphylococcus aureus, Proteus species, Escherichia coli, Haemophilus influenzae, and Neisseria species. Dexamethasone is a potent synthetic corticosteroid with anti-inflammatory, anti-allergic, and immunosuppressive properties. This combination is primarily used to treat inflammatory eye conditions associated with bacterial infections or at risk of bacterial infection.

Brand names
Dexa-GentamicinGenticare DGentamax DMGentapen DOcugentGentakem DGT Cure-DGencin DMBiodexone GGencodex
Other names
gentamicin + dexamethasonedexamethasone + gentamicin eye dropsgentamicin dexamethasonedexa-gentamicin
02

Targets

GR (Glucocorticoid receptor)30S A-site (Bacterial ribosomal 30S A-site)

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