Drug intelligence / Profile preview

gentamicin + procaine + cyanocobalamin

Development stage
Unknown
Lead developer
Anhui Hongye Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Gentamicin procaine vitamin B12 granules is a fixed-dose combination pharmaceutical preparation primarily utilized in China for the treatment of various gastric conditions, including gastritis and related gastropathies. The formulation consists of three active ingredients: gentamicin sulfate, procaine hydrochloride, and vitamin B12 (cyanocobalamin). Gentamicin sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, providing activity against enteric pathogens including *Helicobacter pylori*. Procaine hydrochloride serves as a local anesthetic that rapidly alleviates gastric pain by blocking sodium ion conduction in nerve membranes. Vitamin B12 supports the repair and regeneration of the gastric mucosal epithelium. Together, these components provide a synergistic antibacterial, analgesic, and mucosal protective effect.

Other names
Gentamicin Procaine Vitamin B12 Granules庆大霉素普鲁卡因维B12颗粒
02

Targets

30S A-site (Bacterial ribosomal 30S A-site)NaV (Voltage-gated sodium channels)

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