Drug intelligence / Profile preview

GenTeal Gel

Development stage
Phase 4
Lead developer
Alcon
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

GenTeal Gel is a long-acting ophthalmic lubricant formulation containing 0.3% hypromellose (HPMC) and 0.22% carbomer. It is indicated for the relief of moderate to severe dry eye disease (DED). The formulation features a disappearing preservative, sodium perborate (marketed as GenAqua), which decomposes into water and oxygen upon contact with the tear film and ocular tissue, making it suitable for patients with preservative sensitivities. It works by increasing tear film stability, increasing tear meniscus height, and providing prolonged lubrication to the ocular surface to alleviate symptoms such as foreign body sensation, itching, burning, and dryness.

Brand names
GenTeal GelGenTeal Lubricant Gel Drops
Other names
GenTealGenTeal Tears0.3% HPMC, 0.22% carbomer gel

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