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GEO-MVA
- Development stage
- Unknown
- Lead developer
- GeoVax Labs
- Modality
- Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Recombinant Protein Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Parenteral (injection)
01
Overview
GEO-MVA is a Modified Vaccinia Ankara (MVA)-based vaccine developed by GeoVax Labs for the prevention of Mpox (monkeypox) and smallpox. It is designed as an alternative to existing MVA vaccines, such as Jynneos, and aims to address global supply shortages by offering U.S.-based manufacturing and advanced production processes that increase yield and reduce costs. The vaccine leverages the immunostimulatory properties of the MVA vector to induce protective immunity against orthopoxviruses, including both Mpox and smallpox. GeoVax has successfully manufactured clinical batches of GEO-MVA, with clinical trials anticipated to begin in 2025[2][3][5][7][8]. The company has established strategic partnerships for production scale-up and is working closely with regulatory agencies to expedite approval pathways.
- Brand names
- GEO-MVA
- Other names
- GeoVax MVA vaccine
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