Drug intelligence / Profile preview

Geologie Acne Regimen

Development stage
Unknown
Lead developer
Geologie
Modality
Small Molecules
Administration
Topical
01

Overview

Geologie Acne Regimen is a personalized topical skincare system developed for the treatment and management of acne vulgaris. The regimen primarily incorporates salicylic acid and retinol as its core active pharmaceutical ingredients. Salicylic acid, a beta-hydroxy acid (BHA), functions as a keratolytic agent by promoting the exfoliation of dead skin cells and clearing sebum from pores. Retinol, a vitamin A derivative, undergoes enzymatic conversion within the skin to retinoic acid, which subsequently binds to and activates retinoic acid receptors (RARs). This activation regulates gene expression to normalize follicular keratinization, increase cellular turnover, and reduce the formation of microcomedones. The system is designed to provide a comprehensive approach to acne by combining comedolytic, exfoliative, and anti-inflammatory properties through a multi-step daily routine.

Brand names
Geologie Acne RegimenGeologie Clear System
Other names
Geologie Acne Control System
02

Targets

RARA (Retinoic acid receptor alpha)RARG (Retinoic acid receptor gamma)RARB (Retinoic acid receptor beta)

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