Drug intelligence / Profile preview

German cockroach skin prick solution

Development stage
Phase 3
Lead developer
Wolwo Biotech
Modality
Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Percutaneous
01

Overview

German cockroach skin prick solution is an allergen extract developed by Zhejiang Wolwo Bio-Pharmaceutical for the in vivo diagnosis of Type I hypersensitivity to *Blattella germanica*. It is used in skin prick testing to identify sensitization in patients with suspected allergic rhinitis, allergic conjunctivitis, or other allergic diseases. The solution contains standardized or concentrated proteins extracted from the German cockroach. When introduced into the skin, these allergens cross-link specific IgE antibodies on the surface of mast cells, triggering the release of inflammatory mediators like histamine. This process results in a localized wheal-and-flare reaction, which serves as a diagnostic indicator of allergic sensitization.

Other names
Blattella germanica allergen extractGerman cockroach allergen extract
02

Targets

German cockroach allergen proteinsImmunoglobulin E (IgE) specific to Blattella germanica allergensIgE (Immunoglobulin E)

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