Drug intelligence / Profile preview

Gerovital H3

Development stage
Unknown
Lead developer
Ana Aslan
Modality
Small Molecules
Administration
Intramuscular, Oral
01

Overview

**Gerovital H3** is a Romanian prescription medicinal product originally developed from Ana Aslan's procaine-based geriatric treatment concept. The currently documented Zentiva products contain **procaine hydrochloride** as the sole active pharmaceutical ingredient, including a 100 mg/5 mL intramuscular injection and 100 mg film-coated tablets. Romanian product information lists prophylaxis of age-related degenerative phenomena as its therapeutic indication. Procaine is an ester-type local anesthetic that reversibly inhibits voltage-gated sodium channels; however, the specific mechanism underlying the product's claimed geriatric benefit is not established. A 2024 non-peer-reviewed exploratory study assessed periarticular Gerovital H3 injections with physiotherapy in older adults with knee or hip osteoarthritis, so that use should be considered investigational. ([anm.ro](https://anm.ro/_/_RCP/RCP_14179_24.11.21.pdf))

Brand names
Gerovital H3
Other names
G-H-3G-H3G-H 3G.H.3.GH3GH-3GH 3Gerovital-H3Gerovital-H-3Gerovital-H 3
02

Targets

MAOA (Monoamine oxidase A)

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