Drug intelligence / Profile preview

GeRx-081

Development stage
Preclinical
Lead developer
Gelteq
Modality
Small Molecules, Hydrogel Systems → Drug Delivery Systems
Administration
Oral
01

Overview

GeRx-081 is an oral gel formulation of cannabidiol (CBD) developed by Gelteq. It utilizes Gelteq's proprietary oral gel delivery platform, which is designed to enhance the absorption and bioavailability of lipophilic molecules like cannabinoids. In preclinical studies, GeRx-081 demonstrated a significant increase in bioavailability and higher peak exposure compared to existing FDA-approved oil-based CBD products, despite containing a lower concentration of the active ingredient. The formulation is being developed for medicinal cannabis applications, offering a non-invasive, precise, and convenient alternative to traditional delivery methods such as oils and vapes.

02

Targets

HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CNR1 (Cannabinoid receptor 1)GPR55 (G protein-coupled receptor 55)TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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